Universidad de Sta. Isabel is a private Catholic university founded in 1868 by Vicentian Sisters as the Escuela-Colegio Diocesano de Sta. Isabel. In 1875, the school became the first normal school for women in the country changing its name to Escuela Normal de Maestras of Colegio de Sta. Isabel. It was elevated into its university status in 2001 leading to its current name. It has another campus called
St. Louise De Marillac School of Pili located in Jacob, Naga.
Today, University of Sta. Isabel follows the enhanced basic curriculum offering classes from Kindergarten, Grade school, Junior High, and Senior High School (SHS) with tracks in Academic, Technical-Vocational, and Livelihood, and Arts and Design. The university also boasts of its undergraduate and graduate programs in Nursing, Physical Therapy, Medical Technology, Business Administration, Food Service, Entrepreneurship, Communications, Psychology, Social Work, and Environmental Studies just to name a few. Night classes are also available intended for individuals who cannot take regular classes during the day.